Tale of Two Cities: narrative review of oxygen

نویسندگان

چکیده

The human brain contributes 2% of the body weight yet receives 15% cardiac output and demands a constant supply oxygen (O2) nutrients to meet its metabolic needs. Cerebral autoregulation is responsible for maintaining cerebral blood flow that provides maintains energy storage capacity. We selected administration-related studies published between 1975–2021 included meta-analysis, original research, commentaries, editorial, review articles. In present narrative review, several important aspects effects on tissues are discussed, as well role exogenous O2 administration in patients with chronic ischemic cerebrovascular disease: aimed revisit utility pathophysiological situations whether or not being advantageous. Indeed, compelling clinical experimental evidence questions routine acute post-recovery ischemia, evident by neurophysiology imaging. While still part common practice, it remains unclear use safe.

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ژورنال

عنوان ژورنال: F1000Research

سال: 2023

ISSN: ['2046-1402']

DOI: https://doi.org/10.12688/f1000research.130592.1